Pharmaceutical Technology on MSNOpinion
Advancing single-cell transcriptomics into the mainstream of biomedical research
Kelly Parliament, staff application scientist at Beckman Coulter Life Sciences, discusses how automation is improving the ...
Single-cell RNA transcriptomics allows researchers to broadly profile the gene expression of individual cells in a particular tissue. This technique has allowed researchers to identify new subsets of ...
Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...
This important study advances a new computational approach to measure and visualize gene expression specificity across different tissues and cell types. The framework is potentially helpful for ...
Morning Overview on MSN
New spatial transcriptomics maps gene activity across whole bodies
A wave of spatial transcriptomics studies has produced gene-expression atlases that span entire organs and whole organisms, ...
Capturing spatial information is essential to elucidate how cells function and interact within their native tissue environment. However, the initial spatial transcriptomics techniques have several ...
Jasmine Plummer shares the spatial omics techniques she has developed to investigate the cellular processes underlying ...
Knowing the location of a gene within intact tissue or a single cell allows scientists to unlock unknown cellular functions. This information is often lost in most genetic sequencing techniques, but ...
Using single-cell sequencing and spatial tools, researchers have created the most comprehensive map of the maternal–fetal interface yet.
Exploring biology in its native environment is perhaps the ideal scenario for generating better hypotheses about the cellular interactions that influence—and drive—healthy and diseased states, ...
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